Powerpuff Girls: Super Smash-Up!

The Powerpuff Girls: Super Smash-Up! is a crossover comic miniseries published by IDW Publishing. As the title suggests, the comic focuses on The Powerpuff Girls's regular "team-ups" with various heroes similar to the most well-known version of the original Cartoon Network series. It was released January 28, 2015.

Overview
Each issue of The Powerpuff Girls: Super Smash-Up! features the main characters (Blossom, Bubbles, and Buttercup) teaming up with other characters from the Cartoon Network such as Dexter's Laboratory, Courage the Cowardly Dog, Johnny Bravo and more. Father from kids next door serves as the true main antagonist of The Powerpuff Girls: Super Smash-Up!

Synopsis

 * Issue One: Just when you thought you'd seen it all, Cartoon Network Crossover Craziness continues! After their victory in the Super Secret Crisis War!, the Powerpuff Girls take it easy with a rare VIP tour of Dexter's Laboratory! But when tag-along Dee Dee accidentally activates Dexter's newest invention, the fate of the entire multiverse is suddenly at stake! Plus: a bonus Courage the Cowardly Dog story by the Glyph- and Eisner-nominated Princeless's Jeremy Whitley!
 * Issue Two: The Powerpuff Girls’ inter-dimensional search for Dexter's mutated sister Dee Dee has brought them to the Bagge Farmhouse in the middle of Nowhere! But when they are mistaken for dog sitters, the Girls find themselves thrust into the disturbing nightmare that is Courage's life. Plus, a Foster's Home for Imaginary Friends story—Bloo starts a “Small Club” while Wilt starts a “Tall Club” in response...
 * Issue Three: The Powerpuff Girls follow the monstrously mutated Dee Dee's trail to the world of Cow and Chicken! Too bad Red Guy has gotten to her first! His plan? Make Dee Dee a superstar! Can Cow, Chicken and the Powerpuff Girls reach Dee Dee before she signs her life away?? Plus, a short story featuring The Grim Adventures of Billy and Mandy...and a beauty pageant? That's not gonna be pretty...
 * Issue Four: The Girls have tracked the mutated Dee Dee to Foster's Home for Imaginary Friends! Too bad it's right in the middle of Ultimate Hide n Seek!. Plus, a bonus Mojo Jojo story by Ivan Cohen with art by Nneka Myers! In "No Money, Mojo Problems", Mojo seeks... alternative funding... for his evil deeds.
 * Issue Five: The Powerpuff Girls enlist Mojo Jojo to help them catch Dee Dee in Camp Kidney before the entire multiverse falls apart! What could possibly go wrong? Plus, a puuurrrr-fect bonus Dexter's Laboratory story, Dexter accidentally turns himself into a cat and must try and get Dee Dee to turn him back without being able to communicate.

Characters
The Powerpuff Girls
 * Blossom
 * Bubbles
 * Buttercup
 * Professor Utonium
 * The Mayor
 * Ms. Bellum
 * Talking Dog
 * Mojo Jojo
 * Fuzzy Lumpkins
 * Him
 * Princess Morbucks
 * Gangreen Gang
 * Sedusa
 * Steve the Monster
 * Ya-Mon
 * Narrator

Dexter's Laboratory
 * Dexter
 * Dee Dee
 * Monkey
 * The Justice Friends
 * Major Glory
 * Valhallen
 * Krunk
 * Miss Spell

Courage the Cowardly Dog
 * Courage
 * Muriel
 * Eustace
 * The harvest moon

Foster's Home for Imaginary Friends
 * Mac
 * Bloo
 * Edurado
 * Wilt
 * Coco
 * Mr. Herriman
 * Cheese
 * Duchess
 * Fluffer Nutter
 * Jackie Khones
 * Bloppy Pants
 * Burple Bear
 * New Guy
 * Berry
 * Keystone Blop
 * Uncle Pockets

Cow and Chicken / I Am Weasel
 * Cow / Supercow
 * Chicken
 * Mom
 * Dad
 * Flem
 * Earl
 * Red Guy
 * I.M. Weasel
 * I.R. Baboon

The Grim Adventures of Billy & Mandy
 * Billy
 * Mandy
 * Grim

Camp Lazlo
 * Lazlo
 * Raj
 * Clam
 * Chip
 * Skip
 * Scoutmaster Lumpus

Ed, Edd n Eddy
 * Ed
 * Edd
 * Eddy

Johnny Bravo
 * Johnny Bravo

Codename: Kids Next Door
 * Numbuh 1

Ben 10: Omniverse
 * Ben Tennyson
 * Vilgax

Samurai Jack
 * Jack
 * Scotsman
 * Aku

Trivia

 * Despite being a crossover comic, it is actually part of The Powerpuff Girls franchise.
 * The comic is inspired by the DC Comics Television series Batman: The Brave and the Bold.
 * Jack, Scotsman and Aku made a cameo in the issue 1 of the main "Powerpuff Girls: Super Smash-Up!" chapter.
 * Jack and Aku made a cameo again in the issue 5 of the main "Powerpuff Girls: Super Smash-Up!" chapter, this time they became apes.